Research Projects Page

In the Southern US, HIV prevalence is disproportionately high and PrEP use is disproportionately low. This cross-sectional survey study assessed Tennessee primary care providers’ current PrEP knowledge, attitudes, and prescribing practices with the aim to determine barriers to PrEP provision specific to TN providers.

Ivosidenib is the first approved oral, targeted, small molecule inhibitor of the isocitrate dehydrogenase 1 (IDH1) mutation seen in acute myeloid leukemia. This review article discusses the clinical trials and dose escalation studies conducted to secure the U.S. Food and Drug Administration approval.

This article highlights the challenges in standardizing adherence methodologies as well as the key elements to consider when interpreting adherence results. Specialty pharmacies should consider using adherence measures to identify and intervene on patients with adherence challenges. In addition, integrated specialty pharmacies should work to link adherence to clinical outcomes and healthcare cost savings.

This article discusses development of a quality measures tool to track outcomes for self-injectable biologic therapy used in the management of inflammatory bowel disease. Through a collaborative initiative, a set of clinical and specialty pharmacy quality measures was developed to assess outcomes such as patient safety, disease status, treatment efficacy, and healthcare resource utilization.

This multi-site study evaluated the effectiveness of a clinical pharmacist-driven HCV delivery model in an open system. With an overall sustained virologic response (SVR) rate of 95% (per protocol), the clinical pharmacist-driven HCV treatment model was found to be effective and comparable to other real-world studies with specialist, non-specialist, and non-hepatology providers.

This retrospective cohort analysis of adult patients with PAH prescribed PDE-5I therapy through an integrated model fournd that patients achieved high adherence rates despite almost half reporting side effects and a quarter reporting hospitalization. Median out-of-pocket costs were $14, indicating the important role specialty pharmacists play in ensuring affordable therapy.

Pharmacy technicians facilitate medication refills for patients following transplant by conducting phone calls and scheduling medication shipments. Standard prescribing of these medications required calls to be made every 30 days. However technician’s ability to service an increasing number of patients was limited by high call volume workload. In this study, we found that converting medication supply from 30 to 90-days reduced daily call volume and allowed the technician to service more patients

The objective of this study was to evaluate if medication non-adherence is associated with increased healthcare resource utilization. In patients with moderate-to-severe IBD on self-injectable biologic medication, non-adherence (MPR

This study evaluated the response to adalimumab dose intensification (defined as a change in adalimumab therapy with reinduction or an increase in dosing frequency) in pediatric patients with inflammatory bowel disease.

This evaluation assessed the impact of a pharmacist-managed lithium consult service. Implementation of this service resulted in an increase in obtaining a serum lithium level within 24 hours of hospitalization as well as time savings to providers.